Engineered Livers for Infectious Diseases
نویسندگان
چکیده
منابع مشابه
Engineered Livers for Infectious Diseases
Engineered liver systems come in a variety of platform models, from 2-dimensional cocultures of primary human hepatocytes and stem cell-derived progeny, to 3-dimensional organoids and humanized mice. Because of the species-specificity of many human hepatropic pathogens, these engineered systems have been essential tools for biologic discovery and therapeutic agent development in the context of ...
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Accumulated data based on experiences with curtico,teroids in the management uf infectious diseases, have proved that they are very dfective and ,afe drugs provided that are administered properly. The Corticosteroids arc administered mainly bec,1usc o; antitoxic, antiimflammatory a11d antiallcrgic effects, the cndotoxius are ncuturalized, generalized body reactions are diminished, damaged t...
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Infectious diseases have represented a threat to human lives since the beginning of human existence. Many infectious diseases have been conquered through the discovery of antibiotics and antiviral agents. However, the antibiotic-resistant strains and mutant microorganisms that are now emerging are more powerful than the existing ones. In addition, some existing microorganisms have developed res...
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Gene therapy is being investigated as an alternative treatment for a wide range of infectious diseases that are not amenable to standard clinical management. Approaches to gene therapy for infectious diseases can be divided into three broad categories: (i) gene therapies based on nucleic acid moieties, including antisense DNA or RNA, RNA decoys, and catalytic RNA moieties (ribozymes); (ii) prot...
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ژورنال
عنوان ژورنال: Cellular and Molecular Gastroenterology and Hepatology
سال: 2018
ISSN: 2352-345X
DOI: 10.1016/j.jcmgh.2017.11.005